Recent advances in polysaccharides for osteoarthritis therapy

Eur J Med Chem. 2017 Oct 20;139:926-935. doi: 10.1016/j.ejmech.2017.08.048. Epub 2017 Aug 24.

Abstract

The polysaccharides used in the treatment of osteoarthritis (OA) mainly include sodium hyaluronate, chondroitin sulfate, chitosan, xanthan gum, Low molecular weight heparin, alginate and other polysaccharides. This review summarizes the recent advances in the chemistry and biological activities of polysaccharides for the treatment of OA.

Keywords: Osteoarthritis; Polysaccharides; Therapy.

Publication types

  • Review

MeSH terms

  • Animals
  • Carbohydrate Conformation
  • Humans
  • Osteoarthritis / drug therapy*
  • Polysaccharides / chemistry
  • Polysaccharides / therapeutic use*

Substances

  • Polysaccharides