Outcomes following robotic-assisted laparoscopic prostatectomy: Pentafecta and Trifecta achievements

Minerva Urol Nefrol. 2018 Feb;70(1):66-73. doi: 10.23736/S0393-2249.17.02909-5. Epub 2017 Sep 7.


Background: Functional and oncologic outcomes following radical prostatectomy play a major role in patient satisfaction after treatment. This study was designed to assess the functional and oncologic outcome after robotic assisted radical prostatectomy (RARP) in a single surgeon series of patients.

Methods: A prospectively maintained database of patients undergoing robotic radical prostatectomy in a referral academic center was queried for functional and oncologic outcome. Patients undergoing RARP between 2010 and 2013 were included. Analysis was performed with SPSS and SAS, χ2, Mann-Whitney and t-test were used when appropriate.

Results: Overall, 566 patients were included in the analysis. The Trifecta and Pentafecta was 73.9% and 64.1%, respectively. Patients achieving Pentafecta were younger (P<0.001), had lower PSA level (P=0.04), lower Biopsy Gleason (P<0.01), lower risk prostate cancer (P<0.01) and fewer comorbidities (P=0.03). The patients were followed up for a median of 27.4 months in Trifecta and 20.6 months in Pentafecta group. At 12-month follow-up the continence and potency rate was 90.6% and 84.1%, respectively.

Conclusions: Although preoperative counseling for RARP surgery using Pentafecta criteria offers more precise information and reasonable expectations than using the Trifecta, further research is required to prepare a standard reporting outline.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Humans
  • Laparoscopy / methods*
  • Male
  • Middle Aged
  • Neoplasm Grading
  • Prostate-Specific Antigen
  • Prostatectomy / methods*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / surgery*
  • Retrospective Studies
  • Robotic Surgical Procedures / methods*
  • Treatment Outcome


  • Prostate-Specific Antigen