Green Tea Extracts Epigallocatechin-3-gallate for Different Treatments

Biomed Res Int. 2017;2017:5615647. doi: 10.1155/2017/5615647. Epub 2017 Aug 13.

Abstract

Epigallocatechin-3-gallate (EGCG), a component extracted from green tea, has been proved to have multiple effects on human pathological and physiological processes, and its mechanisms are discrepant in cancer, vascularity, bone regeneration, and nervous system. Although there are multiple benefits associated with EGCG, more and more challenges are still needed to get through. For example, EGCG shows low bioactivity via oral administration. This review focuses on effects of EGCG, including anti-cancer, antioxidant, anti-inflammatory, anticollagenase, and antifibrosis effects, to express the potential of EGCG and necessity of further studies in this field.

Publication types

  • Review

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / therapeutic use*
  • Catechin / analogs & derivatives*
  • Catechin / chemistry
  • Catechin / therapeutic use
  • Humans
  • Inflammation / drug therapy*
  • Neoplasms / drug therapy*
  • Polyphenols / chemistry
  • Tea / chemistry

Substances

  • Antioxidants
  • Polyphenols
  • Tea
  • Catechin
  • epigallocatechin gallate