Cladribine - an old newcomer for pulsed immune reconstitution in MS

Nat Rev Neurol. 2017 Oct;13(10):573-574. doi: 10.1038/nrneurol.2017.119. Epub 2017 Sep 8.


The EMA has approved cladribine tablets for the treatment of multiple sclerosis. The drug is not new, and the journey to its approval has been a long one, but the old concepts that cladribine therapy are based on provide a new option for the possibility of drug-free remission.

MeSH terms

  • Cladribine / administration & dosage
  • Cladribine / pharmacology*
  • Drug Approval
  • Europe
  • Humans
  • Immunologic Factors / administration & dosage
  • Immunologic Factors / pharmacology*
  • Multiple Sclerosis / drug therapy*


  • Immunologic Factors
  • Cladribine