Respiratory support in patients with acute respiratory distress syndrome: an expert opinion

Crit Care. 2017 Sep 12;21(1):240. doi: 10.1186/s13054-017-1820-0.


Acute respiratory distress syndrome (ARDS) is a common condition in intensive care unit patients and remains a major concern, with mortality rates of around 30-45% and considerable long-term morbidity. Respiratory support in these patients must be optimized to ensure adequate gas exchange while minimizing the risks of ventilator-induced lung injury. The aim of this expert opinion document is to review the available clinical evidence related to ventilator support and adjuvant therapies in order to provide evidence-based and experience-based clinical recommendations for the management of patients with ARDS.

Keywords: Esophageal pressure; Extracorporeal membrane oxygenation; Positive end-expiratory pressure; Tidal volume; Ventilator support; Ventilator-induced lung injury; Weaning.

Publication types

  • Review

MeSH terms

  • Expert Testimony / methods*
  • Humans
  • Intensive Care Units / organization & administration
  • Positive-Pressure Respiration / methods
  • Pulmonary Gas Exchange / physiology
  • Respiration, Artificial / methods
  • Respiration, Artificial / trends*
  • Respiratory Distress Syndrome / therapy*
  • Ventilator-Induced Lung Injury / physiopathology
  • Ventilator-Induced Lung Injury / prevention & control