Functional study of Cordyceps sinensis and cordycepin in male reproduction: A review

J Food Drug Anal. 2017 Jan;25(1):197-205. doi: 10.1016/j.jfda.2016.10.020. Epub 2016 Dec 8.


Cordyceps sinensis has various biological and pharmacological functions, and it has been claimed as a tonic supplement for sexual and reproductive dysfunctions for a long time in oriental society. In this article, the in vitro and in vivo effects of C. sinensis and cordycepin on mouse Leydig cell steroidogenesis are briefly described, the stimulatory mechanisms are summarized, and the recent findings related to the alternative substances regulating male reproductive functions are also discussed.

Keywords: Cordyceps sinensis; Leydig cell; cordycepin; male; reproduction; steroidogenesis; testosterone.

Publication types

  • Review

MeSH terms

  • Animals
  • Cordyceps*
  • Deoxyadenosines
  • Male
  • Reproduction


  • Deoxyadenosines
  • cordycepin