Influenza in Older Adults

Infect Dis Clin North Am. 2017 Dec;31(4):757-766. doi: 10.1016/j.idc.2017.07.005. Epub 2017 Sep 12.

Abstract

Annually, influenza viruses cause significant disease in older adults, varying with the virulence of the circulating strain, prior exposure to circulating strain, and influenza vaccine effectiveness. Older adults often present atypically (eg, without fever) and with complications of influenza infection such as chronic obstructive pulmonary disease and congestive heart failure exacerbations. Prevention methods include antiviral medications and vaccines. Current influenza vaccines have moderate effectiveness for the prevention of hospitalization, but newer more immunogenic vaccines designed for adults 65 years of age and older have been licensed.

Keywords: Aging; Antivirals; Influenza; Vaccine.

Publication types

  • Review

MeSH terms

  • Aged
  • Antiviral Agents / therapeutic use
  • Humans
  • Influenza Vaccines / administration & dosage
  • Influenza Vaccines / immunology*
  • Influenza, Human / drug therapy*
  • Influenza, Human / prevention & control*
  • Influenza, Human / transmission
  • Influenza, Human / virology
  • Vaccination*

Substances

  • Antiviral Agents
  • Influenza Vaccines