Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Nov;70(11):917-925.
doi: 10.1136/jclinpath-2017-204601. Epub 2017 Sep 15.

Cutaneous Angiosarcoma: A Current Update

Affiliations
Review

Cutaneous Angiosarcoma: A Current Update

Elina Shustef et al. J Clin Pathol. .

Abstract

Cutaneous angiosarcoma (cAS) is a rare malignant neoplasm with variable clinical presentation. Although a distinct vascular tumour, cAS shares many overlapping histopathological features with other vasoformative and epithelioid tumours or 'mimickers'. cAS shows aggressive behaviour and carries a grave prognosis, thus early diagnosis is of paramount importance to achieve the best possible outcomes. Recently, several genetic studies were conducted leading to the identification of novel molecular targets in the treatment of cAS. Herein, we present a comprehensive review of cAS with discussion of its clinical, histopathological and molecular aspects, the differential diagnosis, as well as current therapies including ongoing clinical trials.

Keywords: angiosarcoma; cutaneous vascular lesions; histologic mimickers; histopathology; immunohistochemistry; molecular and therapy.

Conflict of interest statement

Competing interests: None declared.

Similar articles

See all similar articles

Cited by 10 articles

See all "Cited by" articles

MeSH terms

Substances

LinkOut - more resources

Feedback