Time to Asthma-Related Readmission in Children Admitted to the ICU for Asthma

Pediatr Crit Care Med. 2017 Dec;18(12):1099-1105. doi: 10.1097/PCC.0000000000001336.


Objectives: To compare the time to asthma-related readmissions between children with a previous ICU hospitalization for asthma and those with a non-ICU hospitalization and to explore predictors of time to readmission in children admitted to the ICU.

Design: Retrospective cohort study using a pan-Canadian administrative inpatient database from April 1, 2008, to March 31, 2014.

Setting: All adult and pediatric Canadian hospitals.

Subjects: Children 2-17 years old with a hospitalization for asthma.

Interventions: None.

Measurements and main results: A total of 26,168 children were hospitalized 33,304 times during the study period. The time to readmission was shorter in the ICU group compared with the non-ICU group (median time to readmission 27 mo in ICU vs 35 mo in non-ICU group). Preschool-aged children (hazard ratio, 1.48; 95% CI, 1.02-2.14) and increased length of stay (hazard ratio, 1.63; 95% CI, 1.17-2.27) were associated with a shorter time to readmission.

Conclusions: Children previously admitted to the ICU for asthma had a shorter time to asthma-related readmission, compared with children who did not require intensive care, underlining the importance of targeted long-term postdischarge follow-up of these children. Children of preschool age and who have a lengthier hospital stay are particularly at risk for future morbidity.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Asthma / therapy*
  • Canada
  • Child
  • Child, Preschool
  • Critical Care / statistics & numerical data*
  • Databases, Factual
  • Female
  • Follow-Up Studies
  • Hospitalization / statistics & numerical data
  • Humans
  • Intensive Care Units*
  • Male
  • Multivariate Analysis
  • Patient Readmission / statistics & numerical data*
  • Retrospective Studies
  • Time Factors