Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association

Circulation. 2017 Oct 17;136(16):e232-e268. doi: 10.1161/CIR.0000000000000525. Epub 2017 Sep 18.


Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state of end-organ hypoperfusion that is frequently associated with multisystem organ failure. Despite improving survival in recent years, patient morbidity and mortality remain high, and there are few evidence-based therapeutic interventions known to clearly improve patient outcomes. This scientific statement on cardiogenic shock summarizes the epidemiology, pathophysiology, causes, and outcomes of cardiogenic shock; reviews contemporary best medical, surgical, mechanical circulatory support, and palliative care practices; advocates for the development of regionalized systems of care; and outlines future research priorities.

Keywords: AHA Scientific Statements; delivery of health care; disease management; shock, cardiogenic.

Publication types

  • Review

MeSH terms

  • American Heart Association*
  • Delivery of Health Care, Integrated / organization & administration
  • Health Care Costs
  • Hemodynamics*
  • Humans
  • Patient Selection
  • Phenotype
  • Predictive Value of Tests
  • Regional Health Planning / organization & administration
  • Risk Factors
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / epidemiology
  • Shock, Cardiogenic / physiopathology
  • Shock, Cardiogenic / therapy*
  • Treatment Outcome
  • United States