Does nutrition play a role in the prevention and management of sarcopenia?

Clin Nutr. 2018 Aug;37(4):1121-1132. doi: 10.1016/j.clnu.2017.08.016. Epub 2017 Aug 24.


There is a growing body of evidence that links nutrition to muscle mass, strength and function in older adults, suggesting that it has an important role to play both in the prevention and management of sarcopenia. This review summarises the discussions of a working group [ESCEO working group meeting 8th September 2016] that met to review current evidence and to consider its implications for preventive and treatment strategies. The review points to the importance of 'healthier' dietary patterns that are adequate in quality in older age, to ensure sufficient intakes of protein, vitamin D, antioxidant nutrients and long-chain polyunsaturated fatty acids. In particular, there is substantial evidence to support the roles of dietary protein and physical activity as key anabolic stimuli for muscle protein synthesis. However, much of the evidence is observational and from high-income countries. Further high-quality trials, particularly from more diverse populations, are needed to enable an understanding of dose and duration effects of individual nutrients on function, to elucidate mechanistic links, and to define optimal profiles and patterns of nutrient intake for older adults.

Keywords: Muscle mass; Muscle strength; Nutrition; Physical performance; Sarcopenia; Supplementation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Adult
  • Aged
  • Exercise / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength / physiology
  • Muscle, Skeletal / metabolism
  • Muscle, Skeletal / physiology
  • Nutritional Physiological Phenomena / physiology*
  • Sarcopenia* / physiopathology
  • Sarcopenia* / prevention & control
  • Sarcopenia* / therapy