[Botulinum toxin: An important complement for facial rejuvenation surgery]

Ann Chir Plast Esthet. 2017 Oct;62(5):495-519. doi: 10.1016/j.anplas.2017.07.007. Epub 2017 Sep 19.
[Article in French]


The improved understanding of the functional anatomy of the face and of the action of the botulinum toxin A leads us to determine a new injection procedure which consequently decreases the risk of eyebrow and eyelid ptosis and increases the toxin's injection possibilities and efficiencies. With less units of toxin, the technique herein described proposes to be more efficient on more muscles: variable toxin injections concentration adapted to each injected muscle are used. Thanks to a new procedure in the upper face, toxin A injection can be quite close to an endoscopic surgical action. In addition, interesting results are achievable to rejuvenate the lateral canthus with injection on the upper lateral tarsus, to rejuvenate the nose with injection at the alar base, the jawline and the neck region. Lastly, a smoothing effect on the skin (meso botox) is obtained by the anticholinergic action of the toxin A on the dermal receptors.

Keywords: Botulinum toxin A; Concentration variable; Injection tarsale; Tarsal injection; Toxine botulique A; Variable concentration.

MeSH terms

  • Botulinum Toxins, Type A* / administration & dosage
  • Humans
  • Rejuvenation
  • Rhytidoplasty* / methods


  • Botulinum Toxins, Type A