Patients Less Likely to Lose Weight Following a Knee Replacement: Results From the Osteoarthritis Initiative

J Clin Rheumatol. 2017 Oct;23(7):355-360. doi: 10.1097/RHU.0000000000000579.

Abstract

Background: Knee replacement typically results in reduced pain and improved function, but it is unclear if these improvements lead to weight loss.

Objective: The purpose of this study was to examine weight change patterns preoperatively and postoperatively among overweight/obese knee replacement patients.

Methods: The study evaluated 210 overweight/obese patients from the Osteoarthritis Initiative who underwent a knee replacement during an 8-year longitudinal study. Average annual weight changes during 1- to 2-year intervals prior to, including, and subsequent to knee replacement were categorized as loss (≥-2.5%), maintain (>-2.5% to <2.5%), and gain (≥2.5%). Weight changes across time intervals were compared using logistic regression with generalized estimating equations, adjusting for demographic, health, and knee factors.

Results: On average, patients lost -0.6 kg/y during the interval when the surgery was performed, but weight gain (0.9 kg/y) in the initial postoperative interval represented an overall net weight gain (0.3 kg/y) compared with presurgery. Continued weight gain (0.3 kg/y) was also seen among patients with additional follow-ups. Patients were significantly less likely to have a meaningful weight loss in the time interval immediately following the surgery compared with the interval in which the surgery took place (odds ratio, 0.37; 95% confidence interval, 0.18-0.79).

Conclusions: Overweight and obese patients initially lost weight during the interval including knee replacement; however, they were less likely to lose more than 2.5% of their weight in the 1 to 2 years immediately after the surgery. Knee replacement patients may benefit from weight management interventions both preoperatively and postoperatively.

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Knee* / adverse effects
  • Arthroplasty, Replacement, Knee* / methods
  • Body Mass Index
  • Female
  • Humans
  • Illinois
  • Knee Joint* / diagnostic imaging
  • Knee Joint* / physiopathology
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Obesity* / complications
  • Obesity* / diagnosis
  • Osteoarthritis, Knee* / complications
  • Osteoarthritis, Knee* / diagnosis
  • Osteoarthritis, Knee* / surgery
  • Postoperative Period
  • Risk Factors
  • Statistics as Topic
  • Weight Gain
  • Weight Loss*