Successful treatment of homozygous protein C deficiency by hepatic transplantation

Lancet. 1988 Feb 27;1(8583):435-8. doi: 10.1016/s0140-6736(88)91231-7.

Abstract

A child with homozygous protein C deficiency was treated at age 20 months by orthotopic hepatic transplantation. Postoperatively there was complete reconstitution of protein C activity and resolution of the thrombotic condition.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blood Coagulation Disorders / genetics
  • Blood Coagulation Disorders / therapy*
  • Homozygote
  • Humans
  • Infant
  • Liver Transplantation*
  • Male
  • Protein C / analysis
  • Protein C / genetics
  • Protein C Deficiency*

Substances

  • Protein C