Functional airway obstruction observed with hyperpolarized 129 Xenon-MRI

J Med Imaging Radiat Oncol. 2018 Feb;62(1):91-93. doi: 10.1111/1754-9485.12660. Epub 2017 Sep 22.

Abstract

Hyperpolarized 129 Xenon-MRI (HP 129 Xe MRI) is an emerging imaging modality that allows assessment of both ventilation and gas transfer. Most research to date has focused on non-malignant pulmonary diseases. However, the capability of evaluating the two primary physiological processes of the lung (ventilation and gas transfer) makes HP 129 Xe MRI a promising imaging modality in the management of patients with lung cancer.

Keywords: airway obstruction; gas transfer; hyperpolarized 129Xenon-MRI; lung cancer; magnetic resonance imaging; radiation therapy.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnostic imaging*
  • Adenocarcinoma / pathology
  • Adenocarcinoma / radiotherapy*
  • Airway Obstruction / diagnostic imaging*
  • Bronchoscopy
  • Diagnosis, Differential
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / radiotherapy*
  • Lymphatic Metastasis
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Radiotherapy Planning, Computer-Assisted
  • Tomography, X-Ray Computed
  • Xenon

Substances

  • Xenon