A rare highly aggressive tumour: lymphoepithelioma-like thymic carcinoma

BMJ Case Rep. 2017 Sep 23:2017:bcr2017221478. doi: 10.1136/bcr-2017-221478.

Abstract

Lymphoepithelioma-likethymic carcinoma is a rare neoplasm that presents with compressive symptoms or as an incidental radiological finding of an anterior mediastinal mass. It is an aggressive carcinoma with a high rate of invasion, metastasis and recurrence. Its diagnosis usually carries a poor prognosis largely due to propensity for late diagnosis. To date, guidance for treatment remains limited. This is a case of lymphoepithelioma-like thymic carcinoma in a young male adult who presented initially with back pain. Despite prompt initiation of chemotherapy with cisplatin, doxorubicin and cyclophosphamide, he had a complicated hospital course leading to demise within 2 months of diagnosis.

Keywords: Chemotherapy; Oncology.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma / diagnosis
  • Diagnosis, Differential
  • Humans
  • Low Back Pain / etiology
  • Magnetic Resonance Imaging
  • Male
  • Palliative Care
  • Thymoma / complications
  • Thymoma / diagnosis*
  • Thymoma / diagnostic imaging
  • Thymoma / drug therapy
  • Thymus Neoplasms / complications
  • Thymus Neoplasms / diagnosis*
  • Thymus Neoplasms / diagnostic imaging
  • Thymus Neoplasms / drug therapy
  • Tomography, X-Ray Computed