Orbital atherectomy for the treatment of severely calcified coronary lesions: evidence, technique, and best practices

Expert Rev Med Devices. 2017 Nov;14(11):867-879. doi: 10.1080/17434440.2017.1384695. Epub 2017 Oct 4.


The presence of severe coronary artery calcification is associated with higher rates of angiographic complications during percutaneous coronary intervention (PCI), as well as higher major adverse cardiac events compared with non-calcified lesions. Incorporating orbital atherectomy (OAS) for effective preparation of severely calcified lesions can help maximize the benefits of PCI by attaining maximal luminal gain (or stent expansion) and improve long-term outcomes (by reducing need for revascularization). Areas covered: In this manuscript, the prevalence, risk factors, and impact of coronary artery calcification on PCI are reviewed. Based on current data and experience, the authors review orbital atherectomy technique and best practices to optimize lesion preparation. Expert Commentary: The coronary OAS is the only device approved for use in the U.S. as a treatment for de novo, severely calcified coronary lesions to facilitate stent delivery. Advantages of the device include its ease of use and a mechanism of action that treats bi-directionally, allowing for continuous blood flow during treatment, minimizing heat damage, slow flow, and subsequent need for revascularization. The OAS technique tips reviewed in this article will help inform interventional cardiologists treating patients with severely calcified lesions.

Keywords: Atherectomy; atherectomy technique; coronary artery calcification; coronary artery disease; orbital atherectomy; percutaneous coronary intervention; stents.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Atherectomy, Coronary / instrumentation*
  • Atherectomy, Coronary / methods
  • Clinical Trials as Topic
  • Coronary Angiography
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / surgery*
  • Humans
  • Percutaneous Coronary Intervention / instrumentation*
  • Percutaneous Coronary Intervention / methods
  • Stents
  • Vascular Calcification / diagnostic imaging
  • Vascular Calcification / surgery*