A novel HLA-DRB1 allele, HLA-DRB1*14:127:02, detected in a Chinese hematopoietic stem cell donor

HLA. 2017 Dec;90(6):382-383. doi: 10.1111/tan.13148. Epub 2017 Oct 10.

Authors

J-P Li^{1

2

3

4}, X Zhang^{1

2}, F-Q Lin^{1

2}, K-L Zhang^{1

2}, X-F Li^{1

2

3}

Affiliations

¹ HLA Laboratory, Liaoning Blood Center, Shenyang, China.
² Key Laboratory of Blood Safety Research of Liaoning, Shenyang, China.
³ Shenyang Research Center for Cell Application, Shenyang, China.
⁴ Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.

PMID: 28945321
DOI: 10.1111/tan.13148

Abstract

HLA-DRB1*14:127:02 has one nucleotide change from HLA-DRB1*14:05:01 where Threonine (77) is changed to Asparagine.

Keywords: HLA-DRB1*14:127:02; a novel allele; sequence-based typing.

© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles*
Amino Acid Substitution
Asian People
Base Sequence
Codon / chemistry
Exons*
Gene Expression
Genotype
HLA-DRB1 Chains / genetics*
HLA-DRB1 Chains / immunology
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans
Polymerase Chain Reaction
Polymorphism, Single Nucleotide*
Sequence Alignment
Sequence Analysis, DNA
Tissue Donors*

Substances

Codon
HLA-DRB1 Chains