A prospective survey of neuroleptic malignant syndrome in a short-term psychiatric hospital

Am J Psychiatry. 1988 Apr;145(4):517-8. doi: 10.1176/ajp.145.4.517.

Abstract

Of 1,470 patients treated with neuroleptics during 1 year at a private psychiatric hospital, only one patient developed neuroleptic malignant syndrome--an annual frequency of 0.07%. Use of low doses of neuroleptics may account for this frequency, which is below recent estimates.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects
  • Bipolar Disorder / drug therapy
  • Chlorpromazine / administration & dosage
  • Chlorpromazine / adverse effects
  • Hospitals, Psychiatric*
  • Humans
  • Length of Stay
  • Male
  • Neuroleptic Malignant Syndrome / epidemiology*
  • Neuroleptic Malignant Syndrome / etiology
  • Risk Factors

Substances

  • Antipsychotic Agents
  • Chlorpromazine