The value of molecular techniques to diagnose Ureaplasma urealyticum and Nocardia farcinica pleuropneumonia in a patient with diffuse large B-cell lymphoma

Int J Infect Dis. 2017 Nov;64:93-95. doi: 10.1016/j.ijid.2017.09.015. Epub 2017 Sep 22.


An unusual case of pleural empyema related to Nocardia farcinica and Ureaplasma urealyticum, occurring after autologous haematopoietic stem cell transplantation in a 30-year-old patient with lymphoma, is reported. This case illustrates the role of repeated and comprehensive microbiological investigations and the contribution of molecular techniques in reaching the aetiological diagnosis.

Keywords: Immunocompromised patient; Molecular microbiological diagnosis; Nocardia farcinica; Pleuropneumonia; Ureaplasma urealyticum.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • DNA, Bacterial / analysis
  • Humans
  • Lymphoma, B-Cell / complications*
  • Male
  • Molecular Typing
  • Nocardia
  • Nocardia Infections / complications
  • Nocardia Infections / diagnosis*
  • Nocardia Infections / diagnostic imaging
  • Nocardia Infections / microbiology
  • Pleuropneumonia / complications
  • Pleuropneumonia / diagnosis*
  • Pleuropneumonia / microbiology
  • Polymerase Chain Reaction*
  • Positron Emission Tomography Computed Tomography*
  • RNA, Ribosomal, 16S / analysis
  • Ureaplasma Infections / complications
  • Ureaplasma Infections / diagnosis*
  • Ureaplasma urealyticum* / genetics


  • DNA, Bacterial
  • RNA, Ribosomal, 16S