Gontscharovia popovii, a new source of carvacrol, its polyphenolic constituents, essential oil analysis, total phenolic content and antioxidant activity

Nat Prod Res. 2018 Dec;32(23):2852-2855. doi: 10.1080/14786419.2017.1380020. Epub 2017 Sep 28.

Abstract

The experiment was carried out using the shadow-dried aerial parts including leaves and shoots of Gontscharovia popovii collected in Fars province in order to investigate the polyphenolic compositions, antioxidant activity, total phenolic content and essential oil constituents. The result showed IC50 of 395.77 μg mL-1 and total phenolic content of about 20.01 mg g-1 gallic acid equivalent dry weight. It also showed a wild range of polyphenols such as; Gallic acid, catechin, chloregenic acid, rutin, vanillin, trans-Ferulic acid, sinapic acid, coumarin, hesperedin, quercetin, hesperetin, eugenol and carvacrol as the main detected polyphenols. Some major compounds were also detected through essential oil analysis, such as; 76.7% carvacrol, 4.25% γ-Terpinene, 3.8% p-Cymene and 2.4% (E)-Caryophyllene. Qualitative and quantitative analyses of chemical compounds of G. popovii was performed using HPLC, GC, GC/MS and microplate reader.

Keywords: Gontscharovia popovii; essential oil; polyphenol; radical scavenging activity; total phenolic content.

MeSH terms

  • Antioxidants / analysis*
  • Antioxidants / chemistry
  • Cymenes
  • Gas Chromatography-Mass Spectrometry
  • Lamiaceae / chemistry*
  • Monoterpenes / analysis
  • Oils, Volatile / analysis*
  • Oils, Volatile / chemistry
  • Phenols / analysis
  • Plant Extracts / chemistry*
  • Polyphenols / analysis*

Substances

  • Antioxidants
  • Cymenes
  • Monoterpenes
  • Oils, Volatile
  • Phenols
  • Plant Extracts
  • Polyphenols
  • carvacrol