MWASTools: an R/bioconductor package for metabolome-wide association studies

Bioinformatics. 2018 Mar 1;34(5):890-892. doi: 10.1093/bioinformatics/btx477.


Summary: MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide association studies results.

Availability and implementation: The MWASTools R package is implemented in R (version > =3.4) and is available from Bioconductor:


Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genetic Association Studies
  • Humans
  • Metabolome*
  • Metabolomics / methods*
  • Metabolomics / standards
  • Models, Biological
  • Quality Control
  • Software*