Organization of the dorsal lateral geniculate nucleus in the mouse

Vis Neurosci. 2017 Jan;34:E008. doi: 10.1017/S0952523817000062.


The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the principal conduit for visual information from retina to visual cortex. Viewed initially as a simple relay, recent studies in the mouse reveal far greater complexity in the way input from the retina is combined, transmitted, and processed in dLGN. Here we consider the structural and functional organization of the mouse retinogeniculate pathway by examining the patterns of retinal projections to dLGN and how they converge onto thalamocortical neurons to shape the flow of visual information to visual cortex.

Keywords: Retinal ganglion cells; Retinogeniculate pathway; Thalamocortical neurons; Vision.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Axons
  • Geniculate Bodies / anatomy & histology*
  • Mice
  • Retinal Ganglion Cells / physiology*
  • Visual Cortex / physiology*
  • Visual Pathways / physiology*