Bioimpedance Measurements in Adolescents with Polycystic Ovary Syndrome: A Pilot Study

Adv Exp Med Biol. 2017:987:291-299. doi: 10.1007/978-3-319-57379-3_26.


Limited data are available on the body composition of adolescent women with polycystic ovary syndrome (PCOS). The aim of this study was to examine differences in body composition indices of metabolism, homeostasis and inflammation, between Greek adolescent females suffering from PCOS and age- and body mass index (BMI)-matched non-PCOS controls. Thirteen PCOS patients and nine non-PCOS controls, aged 13-24 years participated in this cross-sectional study. Study participants underwent assessment by a novel dual frequency bioimpedance device (BIA-ACC). The following body composition indices were measured in each adolescent: extra cellular water (ECW) as inflammation marker, total body water (TBW) as homeostasis marker, extracellular mass to body cell mass ratio (ECM/BCM), fat mass (FM), fat-free mass (FFM) and intracellular water (ICW) as markers of body mass composition and metabolism. Non-linear analysis showed no statistically significant differences in the body composition characteristics between PCOS patients and controls. Further studies with larger sample sizes are needed to confirm whether adolescents with PCOS actually have similar body composition profile with their non-PCOS peers.

Keywords: Adolescents; Bioimpedance; Body composition; Homeostasis; Inflammation; Polycystic ovary syndrome.

MeSH terms

  • Adipose Tissue / metabolism
  • Adolescent
  • Biomarkers / metabolism
  • Body Composition*
  • Body Mass Index*
  • Body Water / metabolism
  • Cross-Sectional Studies
  • Electric Impedance*
  • Female
  • Greece
  • Humans
  • Pilot Projects
  • Polycystic Ovary Syndrome / metabolism*
  • Polycystic Ovary Syndrome / physiopathology
  • Young Adult


  • Biomarkers