Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
, 17 (3), 258-261

The Role of Electroencephalography in the Diagnosis of Serotonin Syndrome

Case Reports

The Role of Electroencephalography in the Diagnosis of Serotonin Syndrome

Theeba Krishnamoorthy et al. J Intensive Care Soc.


Serotonin syndrome is a potentially life-threatening side-effect of agents that enhance synaptic serotonin levels. With the increasing use of serotoninergic agents greater awareness of serotonin syndrome is necessary, including the potential for drug interactions with serotoninergic agents to produce serotonin syndrome. Clinical presentation ranges from mild reactions to a severe toxic state involving generalized tonic-clonic seizures, fevers exceeding 40℃ or coma. This case highlights the necessity of considering serotonin syndrome alongside other differential diagnoses: neuroleptic malignant syndrome, infectious cause, atypical seizures and delirium tremens, in the setting of altered mental state with abnormal neurology. It highlights the potential diagnostic use of electroencephalography in supporting a diagnosis of serotonin syndrome.

Keywords: Serotonin syndrome; adverse drug reaction; intensive care; quetiapine; venlafaxine.


Figure 1.
Figure 1.
EEG 1: Abnormal EEG. EEG: electroencephalography.

Similar articles

See all similar articles

Cited by 1 article

Publication types

LinkOut - more resources