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. 2017 Oct 6;66(39):1043-1051.
doi: 10.15585/mmwr.mm6639a3.

Update: Influenza Activity - United States and Worldwide, May 21-September 23, 2017

Lenee Blanton  1 , David E Wentworth  1 , Noreen Alabi  1 , Eduardo Azziz-Baumgartner  1 , John Barnes  1 , Lynnette Brammer  1 , Erin Burns  1 , C Todd Davis  1 , Vivien G Dugan  1 , Alicia M Fry  1 , Rebecca Garten  1 , Lisa A Grohskopf  1 , Larisa Gubareva  1 , Krista Kniss  1 , Stephen Lindstrom  1 , Desiree Mustaquim  1 , Sonja J Olsen  1 , Katherine Roguski  1 , Calli Taylor  1 , Susan Trock  1 , Xiyan Xu  1 , Jacqueline Katz  1 , Daniel Jernigan  1
Affiliations

Update: Influenza Activity - United States and Worldwide, May 21-September 23, 2017

Lenee Blanton et al. MMWR Morb Mortal Wkly Rep. .

Abstract

During May 21-September 23, 2017,* the United States experienced low-level seasonal influenza virus activity; however, beginning in early September, CDC received reports of a small number of localized influenza outbreaks caused by influenza A(H3N2) viruses. In addition to influenza A(H3N2) viruses, influenza A(H1N1)pdm09 and influenza B viruses were detected during May-September worldwide and in the United States. Influenza B viruses predominated in the United States from late May through late June, and influenza A viruses predominated beginning in early July. The majority of the influenza viruses collected and received from the United States and other countries during that time have been characterized genetically or antigenically as being similar to the 2017 Southern Hemisphere and 2017-18 Northern Hemisphere cell-grown vaccine reference viruses; however, a smaller proportion of the circulating A(H3N2) viruses showed similarity to the egg-grown A(H3N2) vaccine reference virus which represents the A(H3N2) viruses used for the majority of vaccine production in the United States. Also, during May 21-September 23, 2017, CDC confirmed a total of 33 influenza variant virus† infections; two were influenza A(H1N2) variant (H1N2v) viruses (Ohio) and 31 were influenza A(H3N2) variant (H3N2v) viruses (Delaware [1], Maryland [13], North Dakota [1], Pennsylvania [1], and Ohio [15]). An additional 18 specimens from Maryland have tested presumptive positive for H3v and further analysis is being conducted at CDC.

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Conflict of interest statement

Conflict of interest: Jacqueline M. Katz reports U.S. Patent 6,196,175 (issued January 2, 2001) for “Preparation and use of recombinant influenza A virus M2 construct vaccine” and U.S. Patent 8,163,545 (issued April 26, 2012) for “An effective vaccine against pandemic strains of influenza viruses.” No other conflicts of interest were reported.

Figures

FIGURE 1
FIGURE 1
Number and percentage of respiratory specimens testing positive for influenza reported by clinical laboratories, by influenza virus type and surveillance week — United States, October 2, 2016–September 23, 2017 * 131,519 (12.3%) of 1,067,211 tested were positive during October 2, 2016–September 23, 2017. † As of September 29, 2017.
FIGURE 2
FIGURE 2
Number of respiratory specimens testing positive for influenza reported by public health laboratories, by influenza virus type, subtype/lineage, and surveillance week — United States, October 2, 2016–September 23, 2017 * N = 42,875. † As of September 29, 2017.
FIGURE 3
FIGURE 3
Genetic characterization of U.S. and international viruses collected during May 21, 2017–September 23, 2017 * As of September 29, 2017.
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