JAKing up resistance to immunotherapy

Sci Immunol. 2017 Oct 6;2(16):eaaq0015. doi: 10.1126/sciimmunol.aaq0015.

Authors

Faisal Alsufyani¹, Shiv Pillai¹

Affiliation

¹ Ragon Institute of MGH, MIT and Harvard Department of Medicine, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA. Email: pillai@helix.mgh.harvard.edu.

PMID: 28986420
DOI: 10.1126/sciimmunol.aaq0015

Abstract

A two-cell type CRISPR screen has identified genes and pathways that mediate resistance to cancer immunotherapy.

Copyright © 2017, American Association for the Advancement of Science.

Publication types

Comment

MeSH terms

Clustered Regularly Interspaced Short Palindromic Repeats
Genes, Essential*
Humans
Immunotherapy
Neoplasms*