Assessment of tobacco heating product THP1.0. Part 1: Series introduction

Regul Toxicol Pharmacol. 2018 Mar;93:1-3. doi: 10.1016/j.yrtph.2017.09.010. Epub 2017 Oct 1.


We have recently developed a Tobacco Heating Product (THP) comprising an electrical heating device, commercially known as Glo™, and consumable tobacco rods, commercially known as Kent Neostiks™. We refer to this system as THP1.0; Bright tobacco-flavoured variant THP1.0(T), or THP1.0(M) Menthol-flavoured variant. In this issue, we present a series of seven pre-clinical studies conducted on THP1.0,covering the following aspects of its design, development, safety and toxicological assessment, and a paper on placing THPs on an emissions continuum.

Keywords: Comprehensive assessment framework; Modified risk tobacco products; Tobacco harm reduction; Tobacco heating product.

Publication types

  • Introductory Journal Article

MeSH terms

  • Electronic Nicotine Delivery Systems / instrumentation*
  • Electronic Nicotine Delivery Systems / methods
  • Flavoring Agents / administration & dosage*
  • Harm Reduction
  • Heating / instrumentation*
  • Humans
  • Tobacco
  • Tobacco Products*


  • Flavoring Agents