Gastric emptying of large single unit dosage forms

J Pharm Pharmacol. 1988 Mar;40(3):205-7. doi: 10.1111/j.2042-7158.1988.tb05220.x.

Abstract

The gastrointestinal transit of two single unit dosage forms has been followed in healthy subjects under different feeding conditions. Transit was affected by the size of the meal administered. When two tablets were given concurrently they often emptied from the stomach at or about the same time, but in a number of cases the two units were seen to empty at widely different times.

MeSH terms

  • Adolescent
  • Adult
  • Chemical Phenomena
  • Chemistry, Physical
  • Food
  • Gastric Emptying*
  • Gastrointestinal Transit
  • Humans
  • Intestine, Small / metabolism
  • Male
  • Tablets

Substances

  • Tablets