Screening and Surveillance of Hepatocellular Carcinoma: An Introduction to Ultrasound Liver Imaging Reporting and Data System

Radiol Clin North Am. 2017 Nov;55(6):1197-1209. doi: 10.1016/j.rcl.2017.06.012.


Given the high prevalence, increasing incidence, and significant morbidity and mortality related to hepatocellular carcinoma (HCC), a robust and cost-effective screening and surveillance program is needed. Most societies recommend ultrasound for HCC screening, despite lack of standardization in imaging acquisition, reporting content and language, and follow-up recommendations. The American College of Radiology Ultrasound Liver Imaging Reporting and Data System (US LI-RADS) fills this unmet need by providing standardization in the use of US in at-risk patients. It is anticipated that US LI-RADS will improve the performance of ultrasound for HCC screening and surveillance and unify management recommendations.

Keywords: HCC; Hepatocellular carcinoma; Reporting; Screening; Surveillance; Ultrasound.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular / diagnostic imaging*
  • Humans
  • Liver / diagnostic imaging
  • Liver Neoplasms / diagnostic imaging*
  • Radiology Information Systems*
  • Ultrasonography / methods*