Refractory Pseudomonas Bacteremia in a 2-Year-Old Sterilized by Bacteriophage Therapy

J Pediatric Infect Dis Soc. 2018 Aug 17;7(3):253-256. doi: 10.1093/jpids/pix056.


Here, we report a complex case that involved a pediatric patient who experienced recalcitrant multidrug-resistant Pseudomonas aeruginosa infection complicated by bacteremia/sepsis; our antibacterial options were limited because of resistance, allergies, and suboptimal source control. A cocktail of 2 bacteriophages targeting the infectious organism introduced on 2 separate occasions sterilized the bacteremia.

Publication types

  • Case Reports

MeSH terms

  • Bacteremia / blood
  • Bacteremia / therapy*
  • Child, Preschool
  • Drug Resistance, Multiple, Bacterial
  • Fatal Outcome
  • Humans
  • Male
  • Phage Therapy* / adverse effects
  • Phage Therapy* / methods
  • Pseudomonas Infections / blood
  • Pseudomonas Infections / therapy*