Vecuronium in the management of tetanus. Is it the muscle relaxant of choice?

Acta Anaesthesiol Belg. 1988;39(2):75-8.


Two cases of severe tetanus admitted to ITU with muscle rigidity and convulsions and needed mechanical ventilation had a continuous infusion of vecuronium as muscle relaxant. The cardiovascular changes of the two patients are described. It is concluded that vecuronium because of its minimal cardiovascular effects is the relaxant of choice in the management of severe tetanus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiovascular System / drug effects
  • Combined Modality Therapy
  • Critical Care
  • Diazepam / administration & dosage
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tetanus / drug therapy*
  • Tetanus / therapy
  • Vecuronium Bromide / administration & dosage
  • Vecuronium Bromide / adverse effects
  • Vecuronium Bromide / therapeutic use*


  • Vecuronium Bromide
  • Diazepam