A novel, tissue-specific, Drosophila homeobox gene

EMBO J. 1988 Jul;7(7):2151-61.

Abstract

The homeobox gene family of Drosophila appears to control a variety of position-specific patterning decisions during embryonic and imaginal development. Most of these patterning decisions determine groups of cells on the anterior-posterior axis of the Drosophila germ band. We have isolated a novel homeobox gene from Drosophila, designated H2.0. H2.0 has the most diverged homeobox so far characterized in metazoa, and, in contrast to all previously isolated homeobox genes, H2.0 exhibits a tissue-specific pattern of expression. The cells that accumulate transcripts for this novel gene correspond to the visceral musculature and its anlagen.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Biological Evolution
  • DNA / genetics
  • DNA / isolation & purification
  • DNA Restriction Enzymes
  • Drosophila / embryology
  • Drosophila / genetics*
  • Embryo, Nonmammalian / physiology
  • Genes, Homeobox*
  • Humans
  • Molecular Sequence Data
  • Organ Specificity
  • Species Specificity
  • Transcription, Genetic

Substances

  • DNA
  • DNA Restriction Enzymes

Associated data

  • GENBANK/Y00843