Patent Ductus Arteriosus closure in preterms less than 2kg: Surgery versus transcatheter

Int J Cardiol. 2018 Jan 1:250:110-115. doi: 10.1016/j.ijcard.2017.10.020. Epub 2017 Oct 6.

Abstract

Background: As new devices come into the market, percutaneous techniques improve and interventionalists become more experienced; percutaneous closure gets more common in preterms. In this study we aimed to compare efficacy and safety of Patent Ductus Arteriosus closure surgically versus transcatheter method in preterms <2kg. Best of our knowledge this study is the first one that compares outcomes of surgery and percutaneous Patent Ductus Arteriosus closure in preterms.

Methods & results: Between the dates July 1997 to October 2014 in our center Patent Ductus Arteriosus of 26 patients <2kg were closed percutaneously (Group A) and 31 less than 2kg operated (Group B). Weight of patients in percutaneous Patent Ductus Arteriosus closure group was significantly more than the surgery group. Mean gestational age of the patients in Group A was 30±1.8weeks, in group B was 28.6±3.5weeks. In group A; all cases were closed successfully except 4 cases: device embolization in 2, cardiac tamponade and iatrogenic aortic coarctation were seen. Pneumomediastinum and chylothorax were the major complications of the surgery group. There was no statistically significance between complication and success rates between two groups.

Conclusion: Percutaneous Patent Ductus Arteriosus closure is the candidate for taking the place of surgery in preterms. However, it is not applied routinely; can only be done in fully equipped large centers by experienced interventionalists.

Keywords: Infant; Patent Ductus Arteriosus; Percutaneous; Surgery.

Publication types

  • Comparative Study

MeSH terms

  • Cardiac Catheterization / methods*
  • Cardiac Catheterization / trends
  • Cardiac Surgical Procedures / methods*
  • Cardiac Surgical Procedures / trends
  • Ductus Arteriosus, Patent / diagnostic imaging*
  • Ductus Arteriosus, Patent / surgery
  • Ductus Arteriosus, Patent / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Low Birth Weight / physiology*
  • Infant, Newborn
  • Infant, Premature / physiology*
  • Male
  • Retrospective Studies
  • Septal Occluder Device / statistics & numerical data
  • Septal Occluder Device / trends