Obesity and Type 2 Diabetes: Two Diseases with a Need for Combined Treatment Strategies - EASO Can Lead the Way

Obes Facts. 2017;10(5):483-492. doi: 10.1159/000480525. Epub 2017 Oct 12.


Obesity is a chronic metabolic disease affecting adults and children worldwide. It has become one of the leading causes of death, as obesity is known to be the main risk factor for a number of non-communicable diseases, in particular type 2 diabetes. This close relationship led to the connotation 'diabesity', highlighting the fact that the majority of individuals with diabetes are overweight or obese. Until today the BMI is still used to classify overweight and obesity. Since reduced muscle mass is highly prevalent throughout the BMI range, the measurement of body composition is strongly recommended. Moreover, it is essential for monitoring the course of weight reduction, which is part of every effective anti-obesity treatment. Weight reduction can be achieved via different weight loss strategies, including lifestyle intervention (diet and exercise), pharmacotherapy, or bariatric surgery. However, not all of these strategies are suitable for all patients, and any further needs should be considered. Besides, attention should also be drawn to concomitant therapies. These therapies may promote additional weight gain and further trigger the deterioration of blood glucose control. Thus, therapeutic strategies are warranted, which can be easily used for the management of obese patients with type 2 diabetes to achieve their glycemic and weight loss goals.

Keywords: Diabesity; Diabetes; Obesity.

Publication types

  • Review

MeSH terms

  • Adult
  • Anti-Obesity Agents / therapeutic use
  • Bariatric Surgery / methods
  • Bariatric Surgery / trends
  • Child
  • Combined Modality Therapy / methods
  • Combined Modality Therapy / trends*
  • Comorbidity
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / therapy*
  • Diet
  • Exercise
  • Health Services Needs and Demand / trends
  • Humans
  • Life Style
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity / therapy*


  • Anti-Obesity Agents