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. 2018 Feb;60(2):174-179.
doi: 10.1097/JOM.0000000000001194.

Exploring Associations Between Postural Balance and Levels of Urinary Organophosphorus Pesticide Metabolites

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Free PMC article

Exploring Associations Between Postural Balance and Levels of Urinary Organophosphorus Pesticide Metabolites

Sunwook Kim et al. J Occup Environ Med. .
Free PMC article

Abstract

Objective: Apply a data-driven approach to explore associations between postural balance and pesticide exposure among Latino farmworkers and non-farmworkers.

Methods: Lasso-regularized, generalized linear models were used to examine associations between postural control measures in four experimental conditions (2 visual × 2 cognitive difficulty) and dialkylphosphate (DAP) urinary metabolite levels.

Results: Obtained models generally performed poorly at explaining postural control measures. However, when both visual and cognitive conditions were altered-the most challenging balance condition-models for some postural balance measures contained several DAP metabolites and had relatively better fits.

Conclusions: The current results were equivocal regarding associations between postural control measures and DAP metabolite concentrations. However, farmworker status appears to be an important variable in understanding this association. Future work should use a posturally- and cognitively-challenging test condition to reveal any potential associations.

Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Coefficients selected by the lasso method for normalized MVML (Top) and CIML (Bottom) obtained from the most challenging condition (eyes-closed and with a concurrent cognitive task). Note that error bars are 95% confidence intervals, CR is urinary creatinine level, and FW is farmworker status.

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