Peripheral nerve injury has remained a substantial clinical complication with no satisfactory treatment options. Despite the great development in the field of microsurgery, some severe types of neural injuries cannot be treated without causing tension to the injured nerve. Thus, current studies have focused on the new approaches for the treatment of peripheral nerve injuries. Stem cells with the ability to differentiate into a variety of cell types have brought a new perspective to this matter. In this review, we will discuss the use of three main sources of mesenchymal stem cells in the treatment of peripheral nerve injuries.
Keywords: Adipose-derived mesenchymal stem cells; Bone marrow mesenchymal stem cells; Cell-based therapies; Mesenchymal stem cells; Peripheral nerve injury; Stem cells; Umbilical cord mesenchymal stem cells.