Delayed-onset MRI findings in acute chorea related to anoxic brain injury

Clin Imaging. Mar-Apr 2018;48:22-25. doi: 10.1016/j.clinimag.2017.10.004. Epub 2017 Oct 5.

Abstract

Anoxic brain injury can manifest with various abnormal movements. We describe acute chorea in a young patient with anoxic brain injury due to chlordiazepoxide toxicity who had delayed radiographic lesions in bilateral globus pallidus. Although brain MRI 8days after the anoxic event was unremarkable, repeat brain MRI 15days after the event showed T2 hyperintensities and enhancement within the bilateral globus pallidi. It is possible that MRI brain findings of bilateral basal ganglia lesions may appear later than onset of chorea in anoxic brain injury. However, given the normal brain MRI in between, other etiologies cannot be excluded entirely.

Keywords: Anoxic brain injury; Basal ganglia; Brain MRI; Chorea; Globus pallidus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Basal Ganglia / diagnostic imaging
  • Basal Ganglia / pathology
  • Brain / diagnostic imaging
  • Brain / pathology*
  • Brain Injuries
  • Chlordiazepoxide / adverse effects*
  • Chorea / diagnostic imaging
  • Chorea / etiology*
  • Globus Pallidus / diagnostic imaging
  • Globus Pallidus / pathology
  • Humans
  • Hypoxia
  • Hypoxia, Brain / chemically induced
  • Hypoxia, Brain / complications*
  • Hypoxia, Brain / diagnostic imaging
  • Magnetic Resonance Imaging / methods
  • Male

Substances

  • Chlordiazepoxide