Disfiguring facial pyoderma vegetans with an excellent outcome

BMJ Case Rep. 2017 Oct 13:2017:bcr2017220779. doi: 10.1136/bcr-2017-220779.


We describe a case of disfiguring facial pyoderma vegetans in order to highlight the challenges in managing this rare skin condition and review the literature.A 54-year-old woman presented to dermatology clinic with a 3-month history of a left-sided facial lesion, which had been treated as an infected sebaceous cyst. The lesion had dramatically increased in size in the weeks prior to presentation. There was a history of Crohn's disease and ileal adenocarcinoma, both of which were in remission. A clinical diagnosis of pyoderma vegetans was made and the patient responded well to immunosuppressive therapy with oral ciclosporin. Carbon dioxide (CO2) laser resurfacing to residual scarring contributed to an excellent cosmetic result.

Keywords: Contraindications And Precautions; Dermatology; Malignant Disease And Immunosuppression; Medical Management; Skin.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma
  • Crohn Disease
  • Cyclosporine / therapeutic use
  • Dermatologic Agents / therapeutic use
  • Diagnosis, Differential
  • Facial Dermatoses / diagnosis*
  • Facial Dermatoses / drug therapy
  • Facial Dermatoses / surgery
  • Female
  • Humans
  • Ileal Neoplasms
  • Laser Therapy
  • Middle Aged
  • Pyoderma / diagnosis*
  • Pyoderma / drug therapy
  • Pyoderma / surgery


  • Dermatologic Agents
  • Cyclosporine