Remission of Crohn's disease after human immunodeficiency virus infection

Gastroenterology. 1988 Dec;95(6):1667-9. doi: 10.1016/s0016-5085(88)80094-5.


A patient with an 18-yr history of Crohn's disease of the colon became infected with the human immunodeficiency virus. The patient had a complete remission of gastrointestinal symptoms in association with progressive immunodeficiency. This finding suggests that CD4 T cells and an intact immune response play a central role in the pathogenesis of Crohn's disease.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / immunology*
  • Adult
  • CD4-Positive T-Lymphocytes / immunology*
  • Crohn Disease / immunology*
  • Humans
  • Male
  • Time Factors