Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia

Am J Psychiatry. 1988 Nov;145(11):1455-6. doi: 10.1176/ajp.145.11.1455.

Abstract

In a study of 135 schizophrenic and 46 manic male patients treated with neuroleptics, a significantly higher proportion of the manic patients (26.1%) than of the schizophrenic patients (5.9%) developed acute dystonia. This suggests a higher vulnerability to acute extrapyramidal symptoms in mania.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Adult
  • Antipsychotic Agents / adverse effects*
  • Basal Ganglia Diseases / chemically induced
  • Bipolar Disorder / drug therapy*
  • Dyskinesia, Drug-Induced / etiology
  • Dystonia / chemically induced*
  • Humans
  • Male
  • Retrospective Studies
  • Schizophrenia / drug therapy*

Substances

  • Antipsychotic Agents