Objective: The objective of this study is to analyze the trend of burden of ischemic heart disease (IHD) in China between 1990 and 2015. Methods: Data were collected from the results of 2015 Global Burden of Disease Study. We arranged and analyzed the mortality and disability-adjusted life year (DALY) for IHD by sexes, ages and provinces (excluding Taiwan, China) in China between 1990 and 2015. The age-standardized rates were determined using the average world population age structure in the period of 2010-2035 as a reference, and the changes of the related indicators were calculated. Results: In 2015, IHD caused 1 461 thousand deaths, and its age-standardized death rate was 114.8 per 100 000. Number of DALYs from IHD were 25 765 thousand in 2015, with the age-standardized DALY rate at 1 760.2 per 100 000. From 1990 to 2015, the age-standardized death rate for IHD in China increased by 13.3% but age-standardized DALY rate decreased by 3.9%. Number of IHD DALYs among male (16 664 thousand) was higher than it among female (9 101 thousand) in China in 2015, and 83.5% of total DALYs from IHD occurred among people aged over 50 years old. Province with highest age-standardized death rate was Heilongjiang, with rate at 187.4 per 100 000 in 2015. Qinghai (54.0%) increased most and Macao (-52.3%) decreased most from 1990 to 2015. Province with highest age-standardized DALY rate was Xinjiang, with rate at 3 040.8 per 100 000 in 2015. Qinghai (33.2%) increased most while Macao (-59.0%) decreased most between 1990 and 2015. Conclusion: Burden of IHD in China increased remarkably from 1990 to 2015, especially among males and people aged over 50 years old. The differences among provinces were obvious.
目的： 研究1990—2015年中国缺血性心脏病（IHD）疾病负担的变化趋势。 方法： 利用2015年全球疾病负担研究结果，整理和分析1990—2015年中国不同性别、年龄、省份（不包括中国台湾）IHD的死亡率、伤残调整寿命年（DALY），以2010—2035年世界人口平均年龄结构为标准人口，计算年龄标化率，并计算相关指标的变化情况。 结果： 2015年，中国IHD死亡146.1万例，标化死亡率为114.8/10万；DALY为2 576.5万人年，标化DALY率为1 760.2/10万。与1990年相比，2015年IHD的标化死亡率上升13.3%，标化DALY率下降3.9%。2015年男性IHD的DALY为1 666.4万人年，高于女性（910.1万人年）；≥50岁人群的DALY占IHD总DALY的83.5%。2015年标化死亡率最高的省份为黑龙江（187.4/10万）；与1990年相比，2015年标化死亡率上升和下降最快的省份分别为青海（54.0%）和澳门特别行政区（-52.3%）。2015年标化DALY率最高的省份是新疆（3 040.8/10万），与1990年相比，2015年标化DALY率上升和下降最快的省份分别为青海（33.2%）和澳门特别行政区（-59.0%）。 结论： 1990—2015年中国IHD疾病负担总体上显著增加，主要危害男性和50岁及以上人群，地区差异明显。.
Keywords: China; Cost of illness; Disability-adjusted life years; Myocardial ischemia.