Beta-blocking drugs and psoriasis. A review of cutaneous side effects and retrospective analysis of their effects on psoriasis

J Am Acad Dermatol. 1988 Nov;19(5 Pt 1):837-41.


beta-Adrenergic receptor blockers have been prescribed widely since their introduction 20 years ago. Noncardiac indications for beta-blockers have been expanded. Dermatologic manifestations of beta-blockers are reviewed in conjunction with their more liberal use. A retrospective analysis of our experience with beta-blockers in patients with psoriasis is presented. A 1-year study of 588 psoriatic patients who received treatment revealed that 26 patients were taking beta-blockers. Exacerbations of psoriasis were noted in 72.4% of these patients. beta-Blockers may worsen psoriasis and should be carefully evaluated in the management of these patients.

MeSH terms

  • Adrenergic beta-Antagonists / adverse effects*
  • Adrenergic beta-Antagonists / therapeutic use
  • Cardiovascular Diseases / drug therapy
  • Drug Eruptions / etiology
  • Humans
  • Psoriasis / chemically induced*
  • Psoriasis / drug therapy
  • Retrospective Studies


  • Adrenergic beta-Antagonists