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. 2018:1672:195-207.
doi: 10.1007/978-1-4939-7306-4_15.

DNA Replication Profiling Using Deep Sequencing

Affiliations

DNA Replication Profiling Using Deep Sequencing

Xanita Saayman et al. Methods Mol Biol. 2018.

Abstract

Profiling of DNA replication during progression through S phase allows a quantitative snap-shot of replication origin usage and DNA replication fork progression. We present a method for using deep sequencing data to profile DNA replication in S. cerevisiae.

Keywords: DNA replication; Deep sequencing; Replication fork rate; Replication forks; Replication origins.

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