Case Series of Successful Postoperative Pain Management in Buprenorphine Maintenance Therapy Patients

Anesth Analg. 2017 Nov;125(5):1779-1783. doi: 10.1213/ANE.0000000000002498.

Abstract

Buprenorphine maintenance therapy patients frequently have severe postoperative pain due to buprenorphine-induced hyperalgesia and provider use of opioids with limited efficacy in the presence of buprenorphine. The authors report good-to-excellent pain management in 4 obstetric patients using nonopioid analgesics, regional anesthesia, continuation of buprenorphine, and use of opioids with high μ receptor affinity.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesia, Obstetrical
  • Analgesia, Patient-Controlled
  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Opioid / administration & dosage*
  • Analgesics, Opioid / adverse effects
  • Anesthetics, Local / administration & dosage
  • Buprenorphine, Naloxone Drug Combination / administration & dosage*
  • Buprenorphine, Naloxone Drug Combination / adverse effects
  • Cesarean Section, Repeat / adverse effects*
  • Drug Administration Schedule
  • Female
  • Humans
  • Narcotic Antagonists / administration & dosage*
  • Narcotic Antagonists / adverse effects
  • Opiate Substitution Treatment / adverse effects
  • Opiate Substitution Treatment / methods*
  • Opioid-Related Disorders / diagnosis
  • Opioid-Related Disorders / physiopathology
  • Opioid-Related Disorders / psychology
  • Opioid-Related Disorders / rehabilitation*
  • Pain Management / adverse effects
  • Pain Management / methods*
  • Pain Measurement
  • Pain Perception / drug effects
  • Pain Threshold / drug effects
  • Pain, Postoperative / diagnosis
  • Pain, Postoperative / physiopathology
  • Pain, Postoperative / prevention & control*
  • Pain, Postoperative / psychology
  • Pregnancy
  • Sterilization, Tubal / adverse effects*
  • Treatment Outcome
  • Young Adult

Substances

  • Analgesics, Non-Narcotic
  • Analgesics, Opioid
  • Anesthetics, Local
  • Buprenorphine, Naloxone Drug Combination
  • Narcotic Antagonists