Purpose: To explore associations between prognostic factors and subtypes of invasive breast cancer (IBC) and elasticity values using three-dimensional (3D) and two-dimensional (2D) shear-wave elastography (SWE).
Materials and methods: Mean elasticity values (kPa) of 121 IBCs were measured using both 3D and 2D SWE. Associations between these values and prognostic factors and subtypes were analyzed using linear regression model.
Results: In both 3D and 2D SWE, larger size and presence of lymphovascular invasion were independent factors influencing higher mean elasticity on multivariate analyses (all p values<0.05).
Conclusions: Using either 3D or 2D SWE, higher mean elasticity values are associated with poor prognostic factors of IBC.
Keywords: Breast neoplasms; Shear-wave elastography; Three-dimensional; Triple negative breast neoplasm; Ultrasound.
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