Effect of baking soda in dentifrices on plaque removal

J Am Dent Assoc. 2017 Nov;148(11S):S4-S9. doi: 10.1016/j.adaj.2017.09.004.


Background: The prevention of dental caries and periodontal diseases targets control of dental plaque biofilm. In this context, chemical agents could represent a valuable complement to mechanical plaque control by reducing and controlling biofilm formation.

Methods: The literature on the effectiveness of different dentifrices has not, however, been carefully categorized. A lack of consensus exists among dental professionals on a recommendation for a universal dentifrice for plaque control. The authors reviewed the scientific data on the different properties of sodium bicarbonate (baking soda)-containing dentifrices and their effectiveness in plaque removal.

Results: The results of the literature search show that baking soda-containing dentifrices are ideal candidates to be considered as a universal dentifrice because baking soda is inexpensive, abundant in supply, highly biocompatible, exhibits specific antibacterial properties to oral microorganisms, has low abrasivity, and is effective in plaque biofilm removal.

Conclusions: Although some patients may benefit from desensitizing or high fluoride-containing dentifrices, those with routine needs may find using dentifrices containing baking soda and fluoride effective.

Practical implications: Baking soda and fluoride dentifrices, therefore, may perhaps be considered as a criterion standard for patients with routine oral hygiene needs.

Keywords: Sodium bicarbonate; bacteria; baking soda; biofilm; dental plaque.

Publication types

  • Review

MeSH terms

  • Dental Plaque / prevention & control*
  • Dentifrices / therapeutic use*
  • Humans
  • Sodium Bicarbonate / therapeutic use*
  • Treatment Outcome


  • Dentifrices
  • Sodium Bicarbonate