Value of neutrophil to lymphocyte and platelet to lymphocyte ratios in pneumonia

Bratisl Lek Listy. 2017;118(9):513-516. doi: 10.4149/BLL_2017_099.

Abstract

Purpose: In our study, we aimed to evaluate neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with Community-acquired pneumonia (CAP).

Methods: This is a retrospective study consisting of 114 patients with CAP and 50 control subjects. Patients with CAP were divided into 2 groups, as inpatient and outpatient.

Results: The main findings of our study were that NLR, PLR and CRP levels were significantly higher in CAP than those in the control group. These biomarkers were also higher in inpatient group than outpatient group, but not statistically significant.

Conclusion: To our knowledge, this is the first study which investigated the role of NLR and PLR as inflammatory biomarkers and the difference in inpatients and outpatients with CAP and their correlation with CRP values in children. However, larger prospective studies are needed to establish their utility as a predictor for the presence of CAP (Tab. 1, Fig. 2, Ref. 9).

Keywords: CRP; inflammatory biomarkers; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio pneumonia..

MeSH terms

  • Biomarkers
  • Blood Platelets / cytology*
  • C-Reactive Protein / metabolism
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Community-Acquired Infections / blood*
  • Female
  • Humans
  • Leukocyte Count
  • Lymphocyte Count
  • Lymphocytes / cytology*
  • Male
  • Neutrophils / cytology*
  • Platelet Count
  • Pneumonia / blood*
  • Retrospective Studies

Substances

  • Biomarkers
  • C-Reactive Protein