Palladium-Catalyzed Synthesis of 1H-Indenes and Phthalimides via Isocyanide Insertion

Xu Wang; Wenfang Xiong; Yubing Huang; Jiayi Zhu; Qiong Hu; Wanqing Wu; Huanfeng Jiang

doi:10.1021/acs.orglett.7b02771

Palladium-Catalyzed Synthesis of 1H-Indenes and Phthalimides via Isocyanide Insertion

Org Lett. 2017 Nov 3;19(21):5818-5821. doi: 10.1021/acs.orglett.7b02771.

Authors

Xu Wang¹, Wenfang Xiong¹, Yubing Huang¹, Jiayi Zhu¹, Qiong Hu¹, Wanqing Wu^{1

2}, Huanfeng Jiang¹

Affiliations

¹ Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
² State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.

PMID: 29064722
DOI: 10.1021/acs.orglett.7b02771

Abstract

A new and versatile multicomponent domino strategy has been developed for the synthesis of a series of 1H-indene and phthalimide derivatives from simple and readily available starting materials. This process operating under mild conditions shows a broad substrate scope with moderate to excellent yields.

Publication types

Research Support, Non-U.S. Gov't