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. 2018 Feb 15;34(4):705-707.
doi: 10.1093/bioinformatics/btx676.

PESTO: Parameter EStimation TOolbox

Free PMC article

PESTO: Parameter EStimation TOolbox

Paul Stapor et al. Bioinformatics. .
Free PMC article


Summary: PESTO is a widely applicable and highly customizable toolbox for parameter estimation in MathWorks MATLAB. It offers scalable algorithms for optimization, uncertainty and identifiability analysis, which work in a very generic manner, treating the objective function as a black box. Hence, PESTO can be used for any parameter estimation problem, for which the user can provide a deterministic objective function in MATLAB.

Availability and implementation: PESTO is a MATLAB toolbox, freely available under the BSD license. The source code, along with extensive documentation and example code, can be downloaded from


Supplementary information: Supplementary data are available at Bioinformatics online.

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